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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LEO1
All Species:
8.79
Human Site:
S171
Identified Species:
17.58
UniProt:
Q8WVC0
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WVC0
NP_620147.1
666
75404
S171
D
E
E
R
A
Q
G
S
D
E
D
K
L
Q
N
Chimpanzee
Pan troglodytes
XP_001170061
606
67985
E131
D
G
G
S
H
H
S
E
A
E
G
S
E
K
A
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_535485
665
75345
S171
D
E
E
R
A
Q
G
S
D
E
D
K
L
Q
N
Cat
Felis silvestris
Mouse
Mus musculus
Q5XJE5
667
75623
S171
D
E
D
R
E
Q
G
S
D
E
D
K
L
Q
N
Rat
Rattus norvegicus
Q641X2
678
76939
D183
E
E
R
E
Q
G
S
D
D
E
K
L
Q
N
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512640
354
40227
Chicken
Gallus gallus
XP_413803
627
71376
Q152
G
K
E
D
K
S
D
Q
S
D
D
E
E
R
Q
Frog
Xenopus laevis
Q52KV5
703
80388
D203
E
Q
E
T
H
Q
S
D
D
E
E
Q
D
N
H
Zebra Danio
Brachydanio rerio
Q6NYV9
696
76423
R171
A
G
S
R
R
S
D
R
G
S
G
S
P
G
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q94546
725
77404
A200
L
Q
I
D
V
E
R
A
N
S
K
S
G
S
R
Honey Bee
Apis mellifera
XP_624295
603
67203
P128
K
E
R
I
S
E
S
P
I
S
P
K
V
T
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781595
591
67675
Q116
E
Q
E
V
E
E
Q
Q
E
E
E
E
E
E
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.9
N.A.
97.7
N.A.
93.4
92.1
N.A.
47.5
78.8
70.9
60.3
N.A.
32.5
36.3
N.A.
42.7
Protein Similarity:
100
90.9
N.A.
99
N.A.
96.5
95.5
N.A.
49.7
86.7
82
69.8
N.A.
49.3
54.9
N.A.
59.4
P-Site Identity:
100
13.3
N.A.
100
N.A.
86.6
20
N.A.
0
13.3
26.6
6.6
N.A.
0
13.3
N.A.
13.3
P-Site Similarity:
100
20
N.A.
100
N.A.
93.3
33.3
N.A.
0
40
60
13.3
N.A.
26.6
33.3
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
0
17
0
0
9
9
0
0
0
0
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
34
0
9
17
0
0
17
17
42
9
34
0
9
0
0
% D
% Glu:
25
42
42
9
17
25
0
9
9
59
17
17
25
9
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
9
17
9
0
0
9
25
0
9
0
17
0
9
9
0
% G
% His:
0
0
0
0
17
9
0
0
0
0
0
0
0
0
9
% H
% Ile:
0
0
9
9
0
0
0
0
9
0
0
0
0
0
0
% I
% Lys:
9
9
0
0
9
0
0
0
0
0
17
34
0
9
9
% K
% Leu:
9
0
0
0
0
0
0
0
0
0
0
9
25
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% M
% Asn:
0
0
0
0
0
0
0
0
9
0
0
0
0
17
25
% N
% Pro:
0
0
0
0
0
0
0
9
0
0
9
0
9
0
0
% P
% Gln:
0
25
0
0
9
34
9
17
0
0
0
9
9
25
9
% Q
% Arg:
0
0
17
34
9
0
9
9
0
0
0
0
0
9
9
% R
% Ser:
0
0
9
9
9
17
34
25
9
25
0
25
0
9
17
% S
% Thr:
0
0
0
9
0
0
0
0
0
0
0
0
0
9
0
% T
% Val:
0
0
0
9
9
0
0
0
0
0
0
0
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _